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Differential diagnosis Rationale for differential diagnosis Research Criteria for diagnosis Immune and Thrombotic TSPP cytolysis, thrombocyto- penia, hyperbilirubi- nemia OAK + platelets; BAK: Total protein, albumin, ALT, AST, bilirubin in fractions, alkaline phosphatase, creatinine, urea, uric acid, LDH, glucose, C – reactive protein; coagulogram; direct Coombs test; myelogram; immunological study; thrombocytopenia up to single ones at normal or even level of megakaryocytes; morphological changes in platelets: an increase in their size, the appearance of low-grain blue cells, as well as their poikilocytosis and a decrease in the process forms of platelets; anemia with significant bleeding; articular syndrome; capatosplenomegaly.
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Differential diagnosis Rationale for differential diagnosis Research Criteria for diagnosis Immune and Thrombotic TSPP cytolysis, thrombocyto- penia, hyperbilirubi- nemia histological biopsy study (spleen, lymph node, iliac crest); ultrasound OBD; consultation of a neurologist myelogram: the number of megakaryocytes, the absence or small number of free platelets, the absence of other changes (signs of tumor growth) in the bone marrow; no signs of hypocoagulation; immunological study: detection of blood antiplatelet platelet associated (Tp A-IgG) antibodies; With thrombotic TSPP: - the presence of neurological symptoms; the formation of multiple blood clots.
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